疯狂飞艇

师资队伍

teaching staff

副高

曹 洋

发布时间 : 2016年06月10日 浏览量 : 1172

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曹洋 博士, 副教授

cy_scu.at.yeah.net(weibimianlajiyoujian,qingba.at.huancheng@)

研究兴趣:

疯狂飞艇1)tansuodanbaizhidexulie、jiegou、gongnengsanzhemiqielianxideaomi

2)tansuorengongshejifeitianrandanbaizhidefangfa,fuyuqishengwuxuetexing

疯狂飞艇3)tansuogaoxiaokaifabaxiangyaowudejisuanfangfa

4)tansuozaishengwushujuhaiyangzhongwajuexinxidefangfa

研究成果:

疯狂飞艇1)tichujiyupengzhuanghuibidezishiyingdiedaisousuosuanfa,bianxiedanbaizhijiegouyuceruanjiancisrr ,gaigongzuobeixieruweispringerchubanshefenzishengwuxuecongshu《protein structure prediction》(disanban)。

2)tichujiyutolman lengthderongjimoxinghesuanfa, keguangfanyongyushushuizuoyongdefenxiyanjiu。

3)tichunaiyaotubianyucesuanfa,yongyuyanjiubaxiangyaowushixiaodefenzijizhi。

4)jianliyaowufenzixunishaixuanjisuanpingtai,bingzaiduiache、mdm2、pbdengduogezhongyaodanbaiyizhijideyanjiuzhongfaxianhuoxingfenzi。

疯狂飞艇5)jianlikangtijisuanfenxipingtai,yongyukangtigaizaohederenyuanhuasheji。

6)canyufazhanleyitaoyijiegoumobanweijichudedanbaizhisanweijiegouyucejisuanpingtai,zai 2010 nianguojidanbaizhijiegouyucebisai casp9 bisaizhong, qudeledangshiguoneilijiecansaixiaozudezuihaochengji(xiaozupaimingdi 9)。

工作经历:

2011-2014,sichuandaxue,shengmingkexuexueyuan,jiangshi

疯狂飞艇2014-jin, sichuandaxue,shengmingkexuexueyuan,fujiaoshou

教育经历:

2016-2017,meiguomixiegendaxue,shengwuxinxixue,fangxue

2004-2010,zhongguokexueyuanshengwuwuliyanjiusuo,shengwuxinxixue,boshi

2000-2004,xinanjiaotongdaxue,yingyongwulixue,xueshi

主要论著:

1. Cao Y*, Li L., Improved protein-ligand binding affinity prediction by using a curvature dependent surface area model,Bioinformatics疯狂飞艇, 30(12):1674-80. 2014

2. Huang L#,Cao Y#, Zhou J, Qin K, Zhu W, Zhu Y, Yang L, Wang D, Wei H*, Shu Y*., A conformational restriction in influenza A virus neuraminidase binding site by R152 caused the combinational effect of I222T with H274Y on oseltamivir resistance.Antimicrob Agents Chemother疯狂飞艇. 58(3), 1639-1645, 2014 (#co-first author)

3. Cao Y, Song L, Miao Z, Hu Y, Tian L, Jiang T*. Improved side-chain modeling by coupling clash-detection guided iterative search with rotamer relaxation.Bioinformatics.27(6): 785-790. 2011

4. Cao Y, Koh X, Dong L, Du X, Wu A, Ding X, Deng H, Shu Y, Chen J, Jiang T*. Rapid Estimation of Binding Activity of Influenza Virus Hemagglutinin to Human and Avian Receptors.PLoS One疯狂飞艇. 6(4):e18664. 2011

5. Guo J#,Cao Y#, Qin K, Zhao X, Wang D, Li Z, Xin L, Shu Y, Zhou J. Limited effect of recombinant human mannose-binding lectin on the infection of novel influenza A (H7N9) virus in vitro.Biochem Biophys Res Commun疯狂飞艇. 458(1):77-81. 2015 (#co-first author)

6. Bu C, Peng B,Cao Y, Wang X, Chen Q, Li J, Shi G. Novel and selective acetylcholinesterase inhibitors for Tetranychus cinnabarinus (Acari: Tetranychidae).Insect Biochem Mol Biol.66:129-35. 2015

7. Miao Z,Cao Y,Jiang T. "Modeling of protein side-chain conformations with RASP",Protein Structure Prediction, 3rd Edition (Methods in Molecular Biology), Edited by D. Kihara, ISBN: 978-1-4939-0365-8 (Print) 978-1-4939-0366-5 (Online). Springer, 2014

8. Larson AM, Wang H,Cao Y, Jiang T, Chen J, Klibanov AM*. Conjugating drug candidates to polymeric chains does not necessarily enhance anti-influenza activity.J Pharm Sci.101(10): 3896-905. 2012

9. Miao Z,Cao Y, Jiang T*. RASP: rapid modeling of protein side chain conformations,Bioinformatics. 27(22): 3117-22. 2011

10. Hu Y, Dong X, Wu A,Cao Y, Tian L, Jiang T*. Incorporation of local structural preference potential improves fold recognition.PLoS One. 6(2): e17215. 2011

11. Zhao Y, Zhang Y,Cao Y,Qi J, Mao L, Xue Y, Gao F, Peng H, Wang X, Gao GF, Ma Y*. Structural analysis of alkaline β-Mannanase from alkaliphilic Bacillus sp. N16-5: implications for adaptation to alkaline conditions.PLoS One.疯狂飞艇6(1): e14608. 2011

12. Du X, Wang Z, Wu A, Song L,Cao Y, Hang H, Jiang T. Networks of genomic co-occurrence capture characteristics of human influenza A (H3N2) evolution.Genome Research疯狂飞艇, 18(1): 178–187, 2008

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