疯狂飞艇

师资队伍

teaching staff

正高

黄 震

发布时间 : 2018年03月30日 浏览量 : 1846

01.jpg

黄震 教授 博导

黄震教授实验室网址: http://www.selab2014.icoc.bz

简介:

黄震教授是中美化学及化学生物学教授协会(CAPA)第一任主席,以及三位创始人之一。他为学术界做了很多工作,为中美学术和科技疯狂飞艇做出了积极贡献。他被选为中国和美国联邦政府研究基金的评审员以及国际多种高端学术刊物的评审员。他曾担任多本书藉刊物的编辑或客座编辑。黄震教授曾就读于四川大学北京大学瑞士苏黎世联邦理工大学,以及哈佛大学医学院,师从2009年诺贝尔医学奖得主杰克·邵斯达克(Jack Szostak)教授。

tashixihesuan、rnahesuanjiyinxinpian、xihesuanshengwupingtaijishujiqixihesuanjingtijiegouyanjiudeduchuangfamingren。tazai《meiguohuaxuehuizazhi》,《deguoyingyonghuaxue》,《hesuanyanjiu》jiqitazhuanyezazhihekanwushangfabiaowenzhang100duopian。tadeyanjiuxiangmuduocihuojiang。tacengdulihuode21xiangyanjiujijin,qizhongbaokuomeiguolianbangzhengfuyanjiujijin、meiguozuozhiyazhouzhengfuyanjiujijin、aizhengyanjiujiechuzhuanjiajijinheqiyejieyanjiujijindezhichi。qiyanjiuxiangmuyijinghuodehuozhengzaishenqingzhongguo、meiguo、ouzhoujiguojizhuanlijifaming(30duoxiang)。tayeshiyongzijifamingdechuangxinjishulaijijituidongdahesuanchanyedefazhanyijishengwuyiyaojishudejinbu。

联系方式:

邮箱: .cn 电话:

简历:

1980-1984nian,huodesichuandaxuexueshixuewei,fenxihuaxuezhuanye

疯狂飞艇1984-1987nian,huodebeijingdaxueshuoshixuewei,shengwuyoujihuaxuezhuanye

1988-1994nian,huoderuishisulishilianbangligongdaxue(eth, zurich)boshixuewei,huaxueshengwuxuezhuanye。

1994-1998nian,hafodaxueyixueyuanyichuanxiboshihou,congshiyu2009niannuobeieryixuejiangdezhushaosidakejiaoshou(professor jack szostak)

1998nian, beipinruniuyuechengshidaxuebulukelunxueyuanweizhulijiaoshou

2004nian, shengweifujiaoshou,bingbeipinruqiaozhiyazhoulidaxuehuaxuexi

疯狂飞艇2009nian, shengweiqiaozhiyazhoulidaxuezhongshenzhengjiaoshou,huodaxuejiechujiaoshoujiang,bingweimeiguozuozhiyazhouaizhengyanjiujiechuyanjiuyuan

2014–jin,sichuandaxueshengmingkexuexueyuanzhengjiaoshou

其他经验和专业成员:

疯狂飞艇2007 – 2010 diyirenzhuxi,zhongmeihuaxuejihuaxueshengwuxuejiaoshouxiehui(capa)

2007 –jin chengyuan,meiguoaizhengyanjiuxiehui

2006 –jin chengyuan,meiguojingtixuexiehui

疯狂飞艇2002-2004 zhuxi,meiguoqingnianhuaxuejiaxiehui(yacs)

疯狂飞艇1997-1998 zhuxi,meiguohuarenshengwuhuaxuejiaxiehui(abc),boshidun

1994-jin chengyuan,meiguohuaxuexuehui

研究方向:

jiegoushengwuxue,huaxueshengwuxue,xibaoshengwuxue,kangaifenzishengwuxueyanjiu,hesuanchuangxinyaowuhexiaofenzichuangxinyaowudefaxian,jibingdekuaisujingzhunhesuanzhenduanyanjiu

研究内容:

疯狂飞艇danbaizhi-hesuankangzhongliuyaowuyanjiu,jibingyijihuanjingweishengwudehesuanjiance, gaoxuanzexingjiyinchenmo,hesuanyaowuchuangxin,gaobaozhenjianjishibieyushengwurnaxinpian,danbaizhi-hesuanyijihesuan-xiaofenzifuhewujingtijiegouyugongnengyanjiu,shengwuhuaxuehechengheyishengwudajiegouweijichudexinyaoyanfa,hesuanshipeitihehemeideshaixuanjigongnengyanjiu,yijixihesuanyijidihesuanchuangxinxingyanjiu。

奖项和专业活动:

2010 –jin zhongguokexuehuaxuebianweihuichengyuan

2008-2013 qiaozhiyazhouaizhengyanjiujiechukexuejiajiang(gcc)

疯狂飞艇2008 qiaozhiyazhoulidaxuejiechujiaoshoujiang

疯狂飞艇2008 qiaozhiyazhoulidaxuejiaoshouchengjiujiang

2008 capajiechujiaoshoujiang

教学经验:

1.hesuandehuaxueheshengwuhecheng,kangaiyaowudefaxian,hesuan-danbaidafenzijiegou,jiliyanjiuhehesuanjiance

2.huaxueheyaowuzhiliao

3.gaojihuaxueshengwuxueheshengwuyoujihuaxue

4.gaojiyoujihechenghejili

部分申请和已获得的专利:

1. Zhen Huang, Title: “RNA MICROCHIP DETECTION USING NANOPARTICLE-ASSISTED SIGNAL AMPLIFICATION”, 2014, PCT, filed.

2. 疯狂飞艇Zhen Huang, Title: “METHODS AND COMPOSITIONS FOR INTERFERENCE WITH DNA POLYMERASE AND DNA SYNTHESIS”, 2013, US provisional application, filed.

3. Zhen Huang, Title: “NANOPARTICLE-ASSISTED RAPID RNA DETECTION ON RNA MICROARRAY”, 2013, US provisional application, filed.

4. 疯狂飞艇Zhen Huang, Title: “Facile SELENIUM CONTAINING NUCLEOSIDES AS NUTRITIONAL SUPPLEMENTS”, 2013, PCT, filed.

5. 疯狂飞艇Zhen Huang, Title: “Facile Synthesis of Natural and Unnatural Nucleoside 5’-Triphosphates”, 2013, Chinese Patent pending.

6. 疯狂飞艇Zhen Huang, Title: “Synthesis of Selenium-Derivatized Nucleosides, Nucleotides, Phosphoramidites, Triphosphates and Nucleic Acids”, 2013, US Patent, 8,354,524.

7. 疯狂飞艇Zhen Huang, Title: “RNA Selective Detection and Quantitation Using Chip and Plate”, 2012, European Patent 1668158.

8. Zhen Huang, Title: “Synthesis of Selenium-Derivatized Nucleosides, Nucleotides, Phosphoramidites, Triphosphates and Nucleic Acids”, 2011, US Patent 12/562,960.

9. 疯狂飞艇Zhen Huang, Title: “Synthesis of Selenium-Derivatized Nucleosides, Nucleotides, Phosphoramidites, Triphosphates and Nucleic Acids”, 2011, US Patent Application (divisional), 13/172,559.

10. Zhen Huang, Title: “Facile Synthesis of Natural and Unnatural Nucleoside 5’-Triphosphates”, 2010, U.S. Provisional Application No.: 61/375,992.

11. Zhen Huang and Jia Sheng, Title: “Improved Method and Process for Synthesis of 2’,3’-Didehyro-2’,3’-dideoxynucleosides (d4Ns)”, 2010, U.S. Patent Application No. 12/933,619 (National Phase Filing of PCT/US09/37823).

12. Zhen Huang, Title: “Facile Synthesis of Natural and Unnatural Nucleoside 5’-Triphosphates”, 2010, US provisional patent, 61/375,560.

13. Zhen Huang, Title: “RNA Detection and Quantitation”, 2010, Oct. 20, European Patent, WO 2005/019469.

14. Zhen Huang, Title: “Ultraviolet and High-Performance Liquid Chromatography Methods for the Evaluation of Sunscreen Efficacy”, 2010, US provisional patent, 61/382,154.

15. Zhen Huang, Jia Sheng, Title: “Novel Compounds and Synthesis of Tellurium-derivatized Oligonucleotides for Structural and Functional Studies”, 2010, PCT/US10/36639.

16. Zhen Huang, Abdalla Hassan, Jia Sheng and Wen Zhang, Title: “Novel Compound and Derivatizaton of DNAs and RNAs on the Nucleobases of Pyrimidines for Function, Structure and Therapeutics”, 2010, PCT/US10/35631.

17. Zhen Huang, Title: “Synthesis of Selenium-Derivatized Nucleosides, Nucleotides, Phosphoramidites, Triphosphates and Nucleic Acids”, 2010, US Patent, US7,982,030.

18. Zhen Huang, Title: “Synthesis of Selenium-Derivatized Nucleosides, Nucleotides, Phosphoramidites, Triphosphates and Nucleic Acids”, 2009, US Patent, US 7,592,446.

19. . Zhen Huang, Abdalla Hassan and Wen Zhang, Title: “Derivatization of DNAs and RNAs at 5-positions of pyrimidines for function, structure, and therapeutics”, 2009, US Provisional Patent Application, 60/180,028.

20. Zhen Huang, Jia Sheng and Abdalla Hassan, Title: “Novel Compounds and Derivatization of DNAs and RNAs at the 2' and 5-positions of pyrimidines with tellurium functionalities for function, structure, imaging, diagnosis, and therapeutics”, 2009, US Provisional Patent Application, 61/182,580.

21. 疯狂飞艇Zhen Huang and Sarah Spencer, Title: “RNA Microchip for Rapid, Direct and Specific Detection of RNAs”, 2009, US Provisional Patent Application, 61/252,940

22. Zhen Huang and Jia Sheng, Title: “Improved Method and Process for Synthesis of 2’,3’-Didehyro-2’,3’-dideoxynucleosides (d4Ns)”, 2009, PCT Patent Application, International application No. PCT/US2009/037823.

23. 疯狂飞艇Zhen Huang, Title: “Se-containing nucleosides, synthesis methods, and anti-cancer activity”, 2008, US Provisional Patent Application, 61/083,815.

代表性论文:

24. Hehua Liu, Xiang Yu, Yiqing Chen, Jing Zhang, Baixing Wu , Lina Zheng, Phensinee Haruehanroengra,Rui Wang, Suhua Li, Jinzhong Lin, Jixi Li, Jia Sheng,Zhen Huang*, Jinbiao Ma *& Jianhua Gan*,“Crystal structure of an RNA-cleaving DNAzyme”, NATURE COMMUNICATIONS,2018, in press(IF: 12.1).

25. Yiqing Yiqing Chen, Jing Zhang, Hehua Liu, Yanqing Gao, Xuhang Li, Lina Zheng, Ruixue Cui, Qingqing Yao, Liang Rong, Jixi Li, Zhen Huang*, Jinbiao Ma* and Jianhua Gan*,“Unique 50-P recognition and basis for dG:dGTP misincorporation of ASFV DNA polymerase X”,PLoS Biology,2017,15, e1002599 (IF:9.797).

26. Zhang, Liu, et al.,Zhen Huang*, Jinbiao Ma*, Jianhua Gan*, “Structural basis for single-stranded RNA recognition and cleavage by C3PO”, Nucleic Acids Research,2016, 44, 9494–9504IF:10.1.

27. Liqin Zhang, Zunyi Yang, Kwame Sefah, Kevin M. Bradley, Shuichi Hoshika, Myong-Jung Kim, Hyo-Joong Kim, Guizhi Zhu, Sena Cansiz, I-Ting Teng, Carole Champanhac,Christopher McLendon, Chen Liu,WenZhang, Dietlind L. Gerloff,Zhen Huang*,Weihong Tan*and Steven A. Benner*,“Evolution of Functional Six-Nucleotide DNA”Journal of American Chemical Society,2015, 137(21),6734−6737 (IF:13.8).

28. Rob Abdur, Oksana O. Gerlits, Jianhua Gan, Jiansheng Jiang, Jozef Salon, Andrey Y. Kovalevsky, Alexander Chumanevich, Irene T. Weber, Zhen Huang*, “Novel Complex MAD Phasing and RNase H Structural Insights by Selenium Oligonucleotides”,Acta Crystallographica Section D,2014,D70, 354-361.

29. Jia Sheng, Jianhua Gan, Alexie Soars, Jozef Salon and Zhen Huang*, “Structural Insights of Non-canonical U•U Pair and Hoogsteen Interaction Probed with Se Atom”,2013,Nucleic Acids ResearchIF:10.1,41(22), 10476-10487.

30. Jia Sheng, Jianhua Gan and Zhen Huang*, “Structure-Based DNA-Targeting Strategies with Small Molecule Ligands for Drug Discovery”,Medicinal Research Reviews,2013,33(5)疯狂飞艇, 1119-1173.

31. Huiyan Sun, Sibo Jiang, Julianne Caton-Williams, Hehua Liu, and Zhen Huang*,“2-Selenouridine Triphosphate Synthesis and Se-RNA Transcription”,RNA,2013,19(9), 1309-1314.

32. Jia Sheng, Wen Zhang, Abdalla E. A. Hassan, Jianhua Gan, Alexei Soares, Song Geng, Yi Ren, Zhen Huang*, "Hydrogen Bond Formation between the Naturally Modified Nucleobase and Phosphate Backbone",Nucleic Acids ResearchIF:10.1,2012,40(16), 8111-8118.

33. Huiyan Sun, Jia Sheng, Abdalla E. A. Hassan, Sibo Jiang, Jianhua Gan and Zhen Huang*,“Novel RNA Base Pair with Higher Specificity using Single Selenium Atom”,Nucleic Acids Res.,2012,40(11)疯狂飞艇, 5171-5179.

34. Wen Zhang, Jia Sheng, Abdalla E. Hassan, and Zhen Huang*, "Synthesis of Novel 2’-Deoxy-5-(Methylselenyl)Cytidine and Se-DNAs for Structure and Function Studies",Chemistry-An Asian Journal,2012,7(3), 476-479.

35. Jia Sheng, Abdalla E. A. Hassan, Wen Zhang, Jianfeng Zhou, Bingqian Xu, Alexei S. Soares and Zhen Huang*, "Synthesis, Structure and Imaging of Oligodeoxyribonucleotides with Tellurium-nucleobase Derivatization",Nucleic Acids Research,2011,39(9), 3962-3971.

36. Wen Zhang and Zhen Huang*, "Synthesis of the 5’-Se-Thymidine Phosphoramidite and Convenient Labeling of DNA Oligonucleotide",Organic Letter,2011,13(8)疯狂飞艇, 2000-2003.

37. Julianne Caton-Williams, Lina Lin,Mathew Smith, and Zhen Huang*, "Convenient Synthesis of Nucleoside 5’-Triphosphates for RNA Transcription",Chemical Communications,2011疯狂飞艇, 47, 8142-8144.

38. Lina Lin, Julianne Caton-Williams, Manindar Kaur, Andres M. Patino, Jia Sheng, Jaya Punetha, and Zhen Huang*, "Facile Synthesis of Nucleoside 5’-(alpha-P-seleno)-triphosphates and Phosphoroselenoate RNA Transcription",RNA,2011疯狂飞艇,17(10),1932-1938.

39. Lina Lin, Jia Sheng, and Zhen Huang*, "Nucleic Acid X-ray Crystallography via Direct Selenium Derivatization",Chemical Society Reviews(invited and peer reviewed),2011,40疯狂飞艇,4591-4602.

40. Khin Lay Maw, Julianne Caton-Williams, Jozef Salon, Zhen Huang*, "Simple UV and HPLC Methods for the Evaluation of Sunscreen Efficacy",Journal of the American Academy of Dermatology,2011,65, 328-335.

41. Abdalla E. A. Hassan, Jia Sheng, Wen Zhang, and Zhen Huang*, "High Fidelity of Base Paring by 2-Selenothymidine in DNA",Journal of American Chemical Society,2010,132疯狂飞艇, 2120-2121. ##

42. Jia Sheng, Abdalla Hassan, Zhen Huang*, "Synthesis of the First Tellurium-Derivatized Oligonucleotides for Structural and Functional Studies",Chemistry - A European Journal,2009,15, 10210-10216.

43. Julianne Caton-Williams and Zhen Huang*, "Synthesis of Colored 4-Selenothymidine Triphosphate and its DNA Polymerase Incorporation into DNAs for Visualization, Structure and Function Studies",Angew. Chem. Int. Ed.,2008,47疯狂飞艇, 1723-1725.

44. Jozef Salon, Jiansheng Jiang, Jia Sheng, Oksana O. Gerlits, Zhen Huang*, "Derivatization of DNAs with Selenium at 6-Position of Guanine for Function and Crystal Structure Studies",Nucleic Acids Research,2008疯狂飞艇, 36, 7009-7018.

45. Jozef Salon, Jia Sheng, Jiansheng Jiang, Guexiong Chen, Julianne Caton-Williams, Zhen Huang*, “Oxygen Replacement with Selenium at the Thymidine 4-position for the Se-Base-Paring and Crystal Structure Studies”, Journal of American Chemical Society,2007, 129, 4862-4863.

46. Jiansheng Jiang, Jia Sheng, Nicolas Carrasco, and Zhen Huang*, “Selenium Derivatization of Nucleic Acids for Crystallography”, Nucleic Acids Research,2007, 35, 477-485.

47. Jozef Salon, Guexiong Chen, Yoani Portilla, Markus W. Germann, and Zhen Huang*, “Synthesis of a Novel 2’-Se-uridine Phosphoramidite and Its Incorporation into Oligonucleotides for Structure Study”,Organic Letters,2005, 7, 5645-5648.

48. Nicolas Carrascoand Zhen Huang*, “EnzymaticSynthesis of Phosphoroselenoate DNA using Thymidine 5’-(a-P-Seleno)-triphosphate and DNA Polymerase for X-ray Crystallography using MAD”,Journal of American Chemical Society,2004,126, 448-449.

49. Nicolas Carrasco, Yuri Buzin, Elizabeth Tyson, Elizer Halpert, andZhen Huang*,Selenium Derivatization and Crystallization of DNA and RNA Oligonucleotides for X-ray Crystallography Using Multiple Anomalous Dispersion”,Nucleic Acids Research,2004,32疯狂飞艇, 1638-1646.

50. Zhen Huang*and Jack W. Szostak, “Evolution of Aptamers with a New Specificity and New Secondary Structures from an ATP Aptamer”,RNA,2003,9, 1456-1463.

51. Quan Du, Nicolas Carrasco, Marianna Teplova, Christopher J. Wilds, Martin Egli, andZhen Huang*, “Internal Derivatization of Oligonucleotides with Selenium for X-ray Crystallography Using MAD”,Journal of American Chemical Society,2002,124, 24-25.

疯狂飞艇_疯狂飞艇彩票_【官网】 幸运28官网_幸运28网站-老品牌最信誉 幸运28官网_幸运28app官网下载_【官网推荐】 大华彩票_大华彩票平台>> 首页 秒速时时彩官网_秒速时时彩软件下载【官方网站】 大华彩票_大华彩票平台官网-官方认证 快乐赛车_快乐赛车投注网址|网站首页 快乐赛车彩票_快乐赛车下载_最佳信誉官网 幸运时时彩_幸运时时彩官方网站【认证官网】 北京pk10_北京pk10赛车_唯一官网 秒速赛车_秒速赛车光大「官方首页」