疯狂飞艇

师资队伍

teaching staff

正高

刘 科

发布时间 : 2012年02月10日 浏览量 : 1420

20005.jpg

刘科,博士,教授,博士生导师

dianziyoujian: .cn

学位简历和工作简历

疯狂飞艇1991.9-1995.6,sichuandaxueshengwuxishengwuhuaxuezhuanyexueshi

疯狂飞艇1995.9-1998.6,sichuandaxueshengwuxishengwuhuaxuezhuanyeshuoshi

疯狂飞艇1998.9-2001.6,zhongguokexueyuanhuaxueyanjiusuohuaxueboshi

2001.10-2005.1,meiguokentajidaxuexibaoyufenzishengwuhuaxuexiboshihou

2010.2-2012.9,meiguotafucidaxueyingyangyushuailaoyanjiuzhongxinboshihou

2005.7-sichuandaxueshengmingkexuexueyuanjiaoshou

yanjiufangxiang:

1.yanghuaxiepoduijitidepohuaiyijijitidefangyuheyingda,shuailaoguochengzhongdanbaizhidesunshanghezhouzhuandaixieyijixiangguanxinhaotonglu。

疯狂飞艇2.guanghezuoyongguanghuaxuefanyingjihuoxingyangziyoujidechanshengyudiaokong。

3.ziyoujishengwujishuzaihuanbao、jiankanghemeironglingyudeyingyong。

yanjiuneirong:

疯狂飞艇jiankangzhangshoushirenleidemeihaoyuanwang。fengkuangfeitingtongguoduizhenhemoshishengwuniangjiujiaomuyijidongwuxibaohedongwumoxingshoumingdiaokongjilideyanjiu,changshichanmingdiaokongdongwuherentishoumingdefenzijizhi。fengkuangfeitingzhuyaoyanjiufansuxitongzaishuailaojishuailaoxiangguanjibingzhongduixibaoneidanbaizhouzhuandaixiedediaokongzuoyong;xibaoneihuoxingyangziyoujidechanshengheduixibaoshoumingdediaokong;yingyanghexiepotiaojianduixibaoshoumingdeyingxiangyijixiangguandanbaijimeicanyudexinhaochuandaotonglu。fengkuangfeitingtongshiyejinlicujinkexueyanjiuzaishehuishengchanzhongdeyingyong,cujinxiangguanlingyudechuangyechuangxin。fengkuangfeitingfeichanghuanyingduifengkuangfeitingyanjiufangxiangganxingqudebenkeshengheshuoshi、boshiyanjiushengjiarufengkuangfeiting,tongshiyereqieqipanyuxiangguanzhuanjiaxuezhekaizhanxueshufengkuangfeiting。

zhuyaofabiaowenzhang:

疯狂飞艇1. qie, b., lyu, z., lyu, l., liu, j., gao, x., liu, y., duan, w., zhang, n., du, l., and liu, k. (2015) sch9 regulates intracellular protein ubiquitination by controlling stress responses. redox biology 5, 290-300

2.Liu, K. *, Lyu, L., Chin, D., Gao, J., Sun, X., Shang, F., Caceres, A., Chang, M. L., Rowan, S., Peng, J., Mathias, R., Kasahara, H., Jiang, S., and Taylor, A*. (2015) Altered ubiquitin causes perturbed calcium homeostasis, hyperactivation of calpain, dysregulated differentiation, and cataract.Proceedings of the National Academy of Sciences of the United States of America112, 1071-1076

3. Shang, F., Wilmarth, P. A., Chang, M. L.,Liu, K., David, L. L., Caceres, M. A., Wawrousek, E., and Taylor, A. (2014) Newborn mouse lens proteome and its alteration by lysine 6 mutant ubiquitin.Journal of proteome research13, 1177-1189

4. Liu, J., Lu, L., Qie, B.-B., andLiu, K.*(2014) Regulation of The Phosphorylation of Yeast Protein Kinase Sch9 Under Environmental Changes and During Chronological Aging.Progress in Biochemistry and Biophysics疯狂飞艇41, 192-201

5. Du, L., Miao, X., Gao, Y., Jia, H.,Liu, K.*, and Liu, Y.* (2014) The protective effects of Trolox-loaded chitosan nanoparticles against hypoxia-mediated cell apoptosis.Nanomedicine : nanotechnology, biology, and medicine疯狂飞艇10, 1411-1420

6. Liu, J., Huang, X., Withers, B. R., Blalock, E.,Liu, K.*, and Dickson, R. C.* (2013) Reducing sphingolipid synthesis orchestrates global changes to extend yeast lifespan.Aging Cell12, 833-841

7. Lin, J., Yu, Y., Shigdar, S., Fang, D. Z., Du, J. R., Wei, M. Q., Danks, A.,Liu, K., and Duan, W. (2012) Enhanced antitumor efficacy and reduced systemic toxicity of sulfatide-containing nanoliposomal doxorubicin in a xenograft model of colorectal cancer.PloS one7, e49277

8. Du, L., Miao, X., Jia, H., Gao, Y.,Liu, K.*, Zhang, X., and Liu, Y.* (2012) Detection of nitric oxide in macrophage cells for the assessment of the cytotoxicity of gold nanoparticles.Talanta101, 11-16

9.贺曾,杜立波,姜玉岗,陈良兵,王广清,田秋,刘科*,杜林方, and刘扬*. (2010)内源性超氧阴离子自由基介导的莱茵衣藻光系统Ⅱ蛋白组分损伤.生物物理学报v.26, 301-308

10.苗敏,曹红平,钟彦,刘军,王一慧,刘昕,张年辉, and刘科*. (2009)出芽酵母Saccharomyces cerevisiae转录抑制因子Rdr1负调控细胞胁迫应答.生物化学与生物物理进展v.36, 1544-1552

11.曹红平,王一慧,钟彦,刘昕,苗敏,刘科*. (2009)过量表达蛋白激酶YPK1使酵母细胞对高盐胁迫的高度敏感依赖于雷帕霉素靶蛋白.微生物学报v.49;No.v.49, 1069-1074

12. Zhang, W., Smith, A., Liu, J. P., Cheung, N. S., Zhou, S.,Liu, K., Li, Q. T., and Duan, W. (2009) GSK3beta modulates PACAP-induced neuritogenesis in PC12 cells by acting downstream of Rap1 in a caveolae-dependent manner.Cellular signalling21, 237-245

13.袁瀚,韩璐,杜立波,田秋,刘科,杜林方,刘扬. (2008)单细胞光合生物莱茵衣藻光系统Ⅱ产生超氧阴离子自由基的ESR研究.生物化学与生物物理进展, 1065-1069

14. Lim, W. G., Chen, X., Liu, J. P., Tan, B. J., Zhou, S., Smith, A., Lees, N., Hou, L., Gu, F., Yu, X. Y., Du, Y., Smith, D., Verma, C.,Liu, K.*, and Duan, W.* (2008) The C-terminus of PRK2/PKNgamma is required for optimal activation by RhoA in a GTP-dependent manner.Archives of biochemistry and biophysics疯狂飞艇479, 170-178

15.Liu, K., Zhang, X., Sumanasekera, C., Lester, R. L., and Dickson, R. C. (2005) Signalling functions for sphingolipid long-chain bases in Saccharomyces cerevisiae.Biochemical Society transactions疯狂飞艇33, 1170-1173

16.Liu, K., Zhang, X., Lester, R. L., and Dickson, R. C. (2005) The sphingoid long chain base phytosphingosine activates AGC-type protein kinases in Saccharomyces cerevisiae including Ypk1, Ypk2, and Sch9.The Journal of biological chemistry280, 22679-22687

17.Liu, K., Sun, J., Song, Y. G., Liu, B., Xu, Y. K., Zhang, S. X., Tian, Q., and Liu, Y. (2004) Superoxide, Hydrogen Peroxide and Hydroxyl Radical in D1/D2/cytochrome b-559 Photosystem II Reaction Center Complex.Photosynthesis research81, 41-47

18. Xu, Y. K., Chen, Z. W., Sun, J.,Liu, K., Chen, W., Shi, W., Wang, H. M., and Liu, Y. (2002) Synthesis, crystal structure, and ESR study of a novel phosphorylated lipophilic spin trap.The Journal of organic chemistry67, 7624-7630

19.刘科,孙健,徐英凯,陈中伟,张启元,张兴康,匡廷云,刘扬. (2001)光系统Ⅱ颗粒内单线态氧诱导产生超氧阴离子自由基.植物学报, 988-990

20.刘科,孙健,刘扬,张启元,匡廷云. (2001)高等植物光系统Ⅱ中强光照射产生超氧阴离子自由基的ESR探索.生物化学与生物物理进展, 372-376

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